Recent advances in the psychopharmacology of major depressive disorder
Alexander L. Young A (2022). Recent advances in the psychopharmacology of major depressive disorder. BJPsych Advances, 29(2), 117-130. https://doi.org/10.1192/bja.2022.14
- Overall rating
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(5.0) 1 review
- Authors
- Laith Alexander, Allan H. Young
- Journal
- BJPsych Advances
- First published
- 2022
- Number of citations
- 6
- Type
- Journal Article
- DOI
- 10.1192/bja.2022.14
Abstract
SUMMARYThis review highlights some of the recent advances in the psychopharmacology of major depressive disorder (MDD). We synthesise evidence on emerging pharmacological therapies targeting the serotonergic system, before exploring several novel treatment targets: the glutamatergic system, the GABAergic system and inflammation. When describing new treatment avenues, we examine the evidence base and how far these new treatments are from routine practice.
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Not Open Access
MauveCartilage
Apr 07, 2026
I really love the figures in this paper, they were very informative. Good, simply explained theories and neuropsychological processes in major depressive disorder, and good discussion of limitations within different models and the different treatments discussed. I enjoyed this paper!